TREATMENT SERUM

The Fast-Acting Serum for Blemishes, Lines and Uneven Tone

iS Clinical Active Serum is the brand’s most popular formula. Physicians call it remarkable, results usually show within days, and a brief cooling tingle tells you it is working from the first application.

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Blue glass bottle of iS Clinical Active Serum with dropper releasing clear liquid on white background
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Botanical Acid Complex

Lactic, glycolic and salicylic acids, all sourced from plants.

Physician Favourite

Described by physicians as remarkable and phenomenal.

Cooling On Contact

A brief tingle on application signals the formula at work.

All Skin Types

Suitable for all skin types and all ages.

THE HERO SERUM

Why Active Serum earns its name

Most serums pick one target. Active Serum works across three: the appearance of fine lines and wrinkles, uneven skin tone, and blemish-prone skin. Its activity comes from botanical acids rather than harsh synthetics, so skin is left moist and smooth, never raw. It suits all skin types and all ages, and it earns its keep quickly, with visible change usually arriving within a couple of days.

Blue glass dropper bottle of iS Clinical Active Serum with white and silver cap on white background
Blue glass bottle of iS Clinical Active Serum with dropper releasing clear liquid on white background
Close-up before and after photos showing skin texture and pigmentation changes over 12 weeks
iS Clinical Active Serum blue glass dropper bottle next to matching blue box on white background
Side-by-side comparison of a woman's jawline and cheek before and after six months of skincare routine

Active Serum

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  • The same product our clinical practitioners use
iS Clinical Active Serum blue glass dropper bottle next to matching blue box on white background

HOW IT WORKS

Three botanical acids, one clear direction

Bilberry brings lactic acid, sugarcane brings glycolic acid and white willow bark brings salicylic acid: a complete AHA and BHA complex sourced from plants. Together they gently resurface, clear congested pores and smooth texture, while mushroom-derived kojic acid brightens the look of uneven tone and vitamin A adds antioxidant support. Expect a cool tingle on application; that is the formula getting to work.

KEY INGREDIENTS

Five botanicals with one job

Every active in the formula, and what each one does for your skin.

  • Vaccinium Myrtillus (Bilberry)

    Vaccinium Myrtillus (Bilberry)

    Fruit/Leaf Extract, source of Lactic Acid. Natural AHA exfoliant with moisturizing properties.

  • Polyporus Umbellatus (Mushroom)

    Polyporus Umbellatus (Mushroom)

    Extract (source of Kojic Acid) Natural antimicrobial that assists in brightening the overall complexion.

  • Saccharum Officinarum (Sugarcane)

    Saccharum Officinarum (Sugarcane)

    Source of Glycolic Acid AHA that gently exfoliates the skin for a renewed complexion.

  • Salix Alba (Willow Bark Extract)

    Salix Alba (Willow Bark Extract)

    Source of Salicylic Acid Botanical BHA that exfoliates the skin and deeply cleans pores.

  • Retinyl Palmitate (Vitamin A)

    Retinyl Palmitate (Vitamin A)

    Natural Vitamin A function as a powerful antioxidant protection, improves collagen & elastin production

HOW TO USE

Two minutes, twice a day

1. Cleanse and pat dry. Actives work best on clean skin.

2. Smooth a thin layer of Active Serum over the face, avoiding the eye area. A brief cooling tingle is normal.

3. Follow with your moisturiser, and SPF every morning.

Blue glass dropper bottle of iS Clinical Active Serum with white and silver cap on white background

Active Serum reviews

In professional hands

Active Serum, answered

What is Active Serum used for?

Active Serum is iS Clinical’s hero treatment serum. It decreases the appearance of fine lines and wrinkles, visibly evens skin tone and is excellent for blemish-prone skin, so one formula covers the jobs several single-purpose serums normally share.

Why does Active Serum tingle when I apply it?

A brief cooling, tingling sensation on application is expected. It is the sign of the formula’s potent botanical activity and settles as the serum absorbs.

How quickly does Active Serum work?

It is a fast-acting formula, and most people notice a visible change within a couple of days. It is also designed for the long term, so results build with continued morning and evening use.

Which acids does Active Serum contain?

Lactic acid from bilberry, glycolic acid from sugarcane and salicylic acid from white willow bark, supported by kojic acid from mushroom extract to brighten the look of uneven tone. Every acid in the formula has a botanical source.

Is Active Serum good for blemish-prone skin?

Yes. The formula is excellent for blemish-prone skin: salicylic acid clears congestion inside the pore while the AHAs smooth the surface and kojic acid works on the marks blemishes leave behind.

Can sensitive skin use Active Serum?

It is formulated for all skin types and all ages, and leaves skin moist and smooth rather than stripped. If your skin is reactive, patch test first and start with once-daily use, building up as your skin settles.

Can I use Active Serum alongside retinol or vitamin C?

Yes, with a sensible routine. Apply Active Serum to clean skin, then layer other products after it. If you are new to acids or retinoids, introduce one active at a time and alternate mornings and evenings while your skin adjusts.

Should I buy the 15ml or the 30ml?

The 15ml is the right way to try Active Serum for the first time or to travel with it. The 30ml costs less per millilitre and is the better buy once you know your skin loves it.

One serum, three jobs done well

Fine lines, uneven tone and blemishes, addressed by one botanical formula.

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